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User: LawsuitGuru

Increased Risk of Bone Fractures in Women Treated with Diabe Two manufacturers of thiazolidinedione drugs, which are used to treat type 2 diabetes, have notified healthcare professionals that women taking these drugs have an increased risk of bone fractures. The first company, GlaxoSmithKline, makes Avandia (rosiglitazone maleate), Avandamet (rosiglitazone maleate and metformin hydrochloride), and Avandaryl (rosiglitazone maleate and glimepiride), which all contain rosiglitazone. In a recent clinical trial, women who took drugs containing rosiglitazone experienced a higher incidence of fractures than those treated with metformin or glyburide therapy. The majority of these fractures were in the upper arm, hand and foot. The second company, Takeda, makes Actos (pioglitazone), ACTOplus met (pioglitazone and metformin hydrochloride), and Duetact (pioglitazone and glimepiride) which all contain pioglitazone. An analysis of the company's clinical trial database showed that drugs that contain pioglitazone may also increase fracture risk in women. The clinical significance of these findings is uncertain at present. Still, both companies recommend that the possibility of fracture be taken into account when rosiglitazone or pioglitazone are considered for treating female patients with type 2 diabetes. Additional Information: FDA MedWatch Safety Alert. Avandia (rosiglitazone maleate), Avandamet (rosiglitazone maleate and metformin hydrochloride), Avandaryl (rosiglitazone maleate and glimepiride). February 21, 2007. http://www.fda.gov/medwatch/safety/2007/safety07.htm#rosiglitazone FDA MedWatch Safety Alert. Actos (pioglitazone) Tablets http://www.fda.gov/medwatch/safety/2007/safety07.htm#Actos Tags: Bone Fracture Women Diabetes Drugs Avandia Avandamet Avandaryl Rosiglitazone FDA Drug Reaction Actos ACTOplus

User: USFoodandDrugAdmin

Stronger Warnings on Avandia and Certain Diabetes Drugs The manufacturers of thiazolidinedione drugs have strengthened warnings about the risks of heart failure with these medications, which are use to treat type 2 diabetes. They are sold as Avandia (rosiglitazone maleate), Avandaryl (rosiglitazone maleate and glimepiride), and Avandamet (rosiglitazone maleate and metformin hydrochloride), which all contain rosiglitazone, and Actos (pioglitazone hydrochloride), Duetact (pioglitazone hydrochloride and glimepride) and Actoplus met, which all contain pioglitazone. The drug labels already had information about heart failure risk, but now there is a new boxed warning that re-emphasizes that these drugs may cause or worsen heart failure in certain patients, and stresses the importance of carefully monitoring patients for signs of heart failure. The labeling recommends that after starting thiazolidinedione therapy or increasing the dose, patients should be observed carefully for the signs and symptoms of heart failure, including excessive, rapid weight gain, shortness of breath, and edema. If any of these signs and symptoms develop and heart failure is confirmed, practitioners should start appropriate management of the heart failure and consider stopping or reducing the dose of the drug. The boxed warning also notes that these drugs are not recommended for patients with symptomatic heart failure, and are specifically contraindicated in patients with NYHA Class III or IV heart failure. FDA Patient Safety News: October 2007 For more information, please see our website: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/psn/transcript.cfm?show=68#2 Tags: Avandia Actos pioglitazone rosiglitazone diabetes heart failure

User: itn

Fans pay tribute to actor Paul Newman Fans from around the world have been paying tribute to US actor Paul Newman, who died of cancer at the age of 83. Tags: hollywood actor paul newman cancer 83 walk of fame

User: poltroy

Michael Learns To Rock - The Actor Michael Learns To Rock - The Actor Tags: Michael Learns To Rock The Actor

User: brendonatkins

Angelina Jolie Inside Actor's Studio Interview (Part 1) Part 1 of 5 of Angelina Jolie's 45+ minute interview on the show Inside Actor's Studio. Tags: angelina jolie interview inside actor studio

User: blacktreemedia

Johnny Depp - 2008 Best Actor Oscar Nominee Johnny Depp Sweeney Todd The Demon Barber of Fleet Street NOMINATED ROLE Johnny Depp plays Sweeney Todd, a barber in Victorian London who embarks on a murderous plan of revenge against the corrupt judge who ruined his life. ACADEMY AWARDS HISTORY This is the third Academy Award nomination for Johnny Depp. He was previously nominated for: * FINDING NEVERLAND (2004) -- Nominee, Actor in a Leading Role * PIRATES OF THE CARIBBEAN: THE CURSE OF THE BLACK PEARL (2003) -- Nominee, Actor in a Leading Role FILM SYNOPSIS In nineteenth-century London, barber Sweeney Todd seeks revenge on the corrupt judge who had him falsely arrested and sent to Australia in an attempt to steal Sweeney's wife. When his plan to kill the judge goes awry, Sweeney begins to murder his clients indiscriminately, with the help of his neighbor, Mrs. Lovett, who disposes of his victims by baking them into meat pies. Tags: entertainment news Academy Award Nominee Oscar Johnny Depp Sweeney Todd Red Carpet

User: myducksvision

Cool Russian Actor! D.I.Y. video about a very cool russian actor, who wants to play a role in american cinema. Very funny :) Tags: fun diy video russian actor stupid reality show lol

User: pakelika420

Dave Chappelle - Inside the Actor's Studio Part 1 Dave Chappelle Tags: Dave Chappelle comedian stand up comic comedy hilarious funny humor lol lmao Chappelle's Show Black Bush

User: theyoungerstatesmen

Actor Hunters Ep. 1 The saga begins...and continues here: Episode 2: http://www.youtube.com/watch?v=B3WLkyJVlW4 Episode 3: http://www.youtube.com/watch?v=4nGxa48Ooz8 Episode 4: http://www.youtube.com/watch?v=6s9a71_iSR0 Tags: Actor Hunters Episode The Younger Statesmen

User: indymogul

Blow your actor in Half : BFX Make sure and watch this episode as we tackle another heavily requested effect...making someone look blown in half! Jam packed with cheap special effects, frisbee fun and a Test Film guest directed by Maniacal Rage! Tags: bfx special effects gore blow in half indymogul maniacal rage

User: yoohouse

2007 MBC Drama Award - Announcing Excellent Actor 30-Dec-2007 MBC Drama Award This cut is announcing the Excellent Actor Award which was won by Gong Yoo and Lee Jun Ki. Gong Yoo's acceptance speech. MC: Nam Sang Mi is giving him a flower bouquet. Yoon Eun Hye looks like she doesn't know what to do because Nam Sang Mi went to go give flowers! GY: It's okay, it's okay! You don't have to come! MC: She's coming up! MC: She's here with flowers. Congratulations! Why don't we hear a speech from you, Gong Yoo ssi? GY: I was dressing up, and I wore this khaki-coloured suit. It's a colour I'm going to be wearing a lot now. After I debuted... I don't know if this is arrogant or not... but I've never thought of wanting to win an award. But now that I've won, and I'm on stage... it feels good. I want to thank my lovely mom who still loves when I come out on TV and is watching me right now, and my father, who was the one to receive the most autographs from Coffee Prince. And I want to share this honor with the Coffee Prince family, and I love the Yoo & I fan club who are freezing outside. Also, to everybody that I love... be happy and healthy. Thank you! after Lee JunKi's speech... MC: Wait, wait! Gong Yoo ssi, just like you said, you are going to be wearing khaki a lot from now on. A lot of fans are sad because you have to leave for the military. To be exact, when will you be leaving? Is today your last TV appearance? GY: Yes, formally, today would be the last. MC: Oh, I see. Then what exact day...? GY: Oh, when I'm leaving? On January 14th, I'll start my training. (i'm not 100% that's what he says) MC: Oh no!! GY: I'll return safely! MC: Gong Yoo ssi! A lot of fans must be sad right now. Can you give some words to your loving fans as well as Yoon Eun Hye and the Coffee Prince team? GY: Yes. Our director really wanted Eun Hye and I to win the Best Couple award, so it's a bit disappointing. And I don't know where she is right now, but I didn't get to say thank you... so thank you to our director. Um, I've never won an award before, so I'm kind of shaking from nervousness. Anyway, I'll be going to the military and coming back very healthy. Please don't forget me, and please remember me. Be healthy and happy! Translation by mishybear@Soompi and YEHbaby@Soompi for posting. Tags: gong yoo 공유 孔侑

User: AssociatedPress

'Harry Potter' Actor Killed in London Stabbing SelectPlus'Harry Potter' Actor Killed in London Stabbing'Harry Potter' Actor Killed in London StabbingThe Associated PressEighteen-year-old Rob Knox, who plays Marcus Belby, in the upcoming film 'Harry Potter and the Half-Blood Prince' was stabbed in a brawl. One of the men injured in the fight was arrested on suspicion of murder. (May 25)[Notes:ANCHOR VOICE] [Notes:PHOTO OF KIDS IN LINE WITH BOOK]THE TRAGIC DEATHS FROM THE HARRY POTTER BOOK SERIES ARE SUPPOSED TO BE IMAGINARY. [Notes:PHOTO OF TEEN]BUT A REAL-LIFE ACTOR FROM THE UPCOMING MOVIE IS NOW DEAD. [Notes:7. SOUNDBITE: (English) Callum Turner, friend: (first words overlaid by previous shot):]"I knew he was serious because he looked into my eyes and said 'Callum, I need help, I need you to help me.' I sat him down and I laid him on the floor. I laid him down. I was just holding his hand, holding his head in my hands. I was trying to talk to him, keep him calm." [Notes:CONDOLENCE SHOTS OUTSIDE PUB]POLICE SAY 18-YEAR-OLD ROB KNOX WAS STABBED TO DEATH DURING A BRAWL IN LONDON ON SATURDAY. THE BRITISH ACTOR PLAYS MARCUS BELBY IN "HARRY POTTER AND THE HALF-BLOOD PRINCE". WARNER BROTHERS STUDIOS SAYS IT IS SHOCKED BY THE NEWS OF HIS DEATH. SO FAR THIS YEAR 14 LONDON TEENS HAVE DIED VIOLENTLY . THE RECENT SURGE HAS SPARKED LONDONERS OUTRAGE. [Notes:11. SOUNDBITE: (English) Callum Turner, friend: (first words overlaid by previous shot):]"People running round with knives. They don't realise the value of life - sickening. That's someone's life, that's a boy's life. OFFICIALS SAY FIVE YOUNG MEN WERE INJURED IN THE FIGHT. ONE OF THEM WAS A 21-YEAR-OLD WHO WAS ARRESTED ON SUSPICION OF MURDER. ___ ___, The Associated Press.(****END****) (ANCHOR VOICE:SKozell-------------------------VIDEO PRODUCER: NHawkins------------------------------VIDEO SOURCE: GVW--------------------------VIDEO APPROVAL: DBruns------------------------------VIDEO RESTRICTIONS: No Access UK----------------------------------SCRIPT/WIRE SOURCE: AP------------------------------------) Tags: ukk stabbing 'harry potter' actor killed london

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